L-Serine and L-threonine dehydratase from Clostridium propionicum Two enzymes with different prosthetic groups
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چکیده
منابع مشابه
Isolation and Properties of a Homogeneous Preparation of Cystathionine Synthetase-l-serine and L-threonine Dehydratase.
Selim and Greenberg (1, 2) achieved a considerable degree of purification of L-serine dehydratase (L-serine hydro-lyase (deaminating), EC 4.2.1.13) from rat liver and demonstrated that this protein preparation contained the cystathionine-synthesizing activity of the liver (L-serine hydro-lyase (adding L-homocysteine), EC 4.2.1.21). These workers (2) also observed activity of their enzyme prepar...
متن کاملRegulation of hepatic L-serine dehydratase and L-serine-pyruvate aminotransferase in the developing neonatal rat.
1. The activities of l-serine dehydratase and l-serine-pyruvate aminotransferase were determined in rat liver during foetal and neonatal development. 2. l-Serine-pyruvate aminotransferase activity begins to develop in late-foetal liver, increases rapidly at birth to a peak during suckling and then decreases at weaning to the adult value. 3. l-Serine dehydratase activity is very low prenatally, ...
متن کاملL-serine specific dehydrase from Clostridium acidi-urici.
Formation of serine and pyruvate as intermediates in uric acid fermentation by Clostridium acidi-urici was suggested by Radin and Barker (1953), Sagers and Beck (1956), and Rabinowitz and B3arker (1956) to account for the labeling of acetate formed from C14-labele(d purines, and from the ability of cell suspensions and extracts to deaminate serine to pyruvate and ammonia. The present communicat...
متن کاملInduction of L-serine dehydratase in Aeromonas punctata.
L-Serine dehydratase (SD) was produced to the extent of only 0·04 international unit (iu) per mg dry weight by Aeromollas pUllctata NRRL B-928 when grown on a chemically defined medium. Addition of 2% (w/v) L-serine to this medium increased SD ten-fold or more, indicating a significant inductive effect. o-Serine was toxic to the organism, making weights and enzyme titres uncertain, but DL-serin...
متن کاملBacterial Threonine Aldolase and Serine Hydroxymethyltransferase Enzymes
for the enzyme in vivo unless an alkaline micro-environment was postulated or conditions were present in vivo which could potentiate inhibition by UMP at near-neutral pH (Yon, 19726). Substances such as deoxycholate which can bind to the hydrophobic site on the enzyme may provide such potentiation. Fig. 2 shows the effects of UMP and deoxycholate at pH values between 7 and 11. In the absence of...
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ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1993
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1993.tb18040.x